Marathon negotiations between the United States and Iran concluded without an agreement on Saturday. Vice President Vance made the announcement during a press conference in Islamabad, Pakistan. The failure to reach a deal immediately places a recently established ceasefire in jeopardy.

The diplomatic deadlock follows a two-week pause in hostilities that was agreed upon just last week. This round of talks was seen as a critical test for sustaining that temporary peace. The lack of progress now raises the specter of a swift return to conflict.